Melanotan 2 -
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Melanotan 2 information:
Melanotan 2 is set to revolutionise everyone's tanning needs for the future.
It is a hormonal peptide which induces the skins natural tanning system to produce a protective tan prior to UV exposure.
Melanotan has been under development since the mid 1980's by the University of Arizona where reserchers there knew that one of the best defences against skin cancer was a natural tan.
Melanotan II will do this by stimulating the body's natural tanning mechanism to create a tan without first needing exposure to harmful levels of UV radiation.
Because skin cancer (melanoma) today is a major health concern, Melanotan II is expected to be used to combat it, producing a natural sunless tan and affording protection for those who would otherwise burn or have difficulty in tanning.
Melanotan and Melanotan II are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (a-MSH) that tend to induce skin tanning. Unlike melanotan though, Melanotan II Has the additional effect of increasing libido.
Both drugs were developed at the University of Arizona. Researchers there knew that one of the best defences against skin cancer was a natural tan which has been slowly developed over weeks.
They hypothesized that an effective way to reduce skin cancer rates in people would be to induce the body's natural tanning system to produce a protective tan prior to UV exposure. They knew the body's naturally occuring hormone alpha-melanocyte stimulating hormone (a-MSH) causes melanogenesis, a process by which the skin's tanning cells (melanocytes) produce the skin's tanning pigment (melanin). With that knowledge they tested to see if administering this hormone to the body directly could be an effective method to cause sunless tanning. What they found was that while it appeared to work, natural alpha-MSH had too short a half life in the body to be practical as a theraputic drug. So they decided to try and find a more potent and stable alternative, one that would be more practical.
After synthesizing and screening hundreds of molecules, the researchers headed by Dr Victor Hruby, found a peptide that after trials and testing seemed to not only be safe but also approximately 1,000 times more potent than natural a-MSH. They dubbed this new peptide Melanotan II. However this still has to be given as a subcutaneous injection.
Since their discovery, numerous studies dating back to the mid-1980's have shown no obvious toxic effects of Melanotan. Because skin cancer (melanoma) today is a major health concern, Melanotan II is expected to be used to combat it. Melanotan II will do this by stimulating the body's natural tanning mechanism to create a tan without first needing exposure to harmful levels of UV rediation. This in turn will reduce the potential for skin damage that can eventually lead to skin cancer.
Melanotan 2 Trial:
Having discovered MT 2 from articles and research on the internet the writer decided to test the drug with a view to its effectivness in respect of sunless tanning, and resulting side effects.
The trial was conducted on a female subject aged 50, over a period of 17 days. Prior to which no exposure to the sun or artificial UV had taken place in the preceding 6 weeks or indeed during the trial period. Skin coulouration for the subject being normal.
During the course of the research blood pressure, heart rate, weight, local reaction to injections and side effects were monitored. It was found that blood pressure, heart rate and weight remained normal for the subject. The only adverse side effects noted were occasional minor local reaction at the injection site (resembling an insect bite) which disappeared within a few minutes. and very mild nausea in the early stages.
Other effects which were observed during the trial were darkening of freckles and moles. This again from reading articles by others who have researched and used MT II appears to be a normal side effect, attributed to the increase of the skins tanning pigment, melanin.
Photo's were taken at the commencement of the trial, at day 9 and at the conclusion (of what has been termed the "loading cycle") following one 6 min sun bed session which appears to the writer to act as a developer for the MT 2.
The results were indeed very good as can seen in the photo's which the writer had taken and can confirm are absolutely genuine.
The writer can only conclude from personal knowledge that the MT 2 is as effective in the respect of sunless tanning as the research suggests.